RNA helicase domains of viral origin in proteins of insect retrotransposons: possible source for evolutionary advantages

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RNA helicase domains of viral origin in proteins of insect retrotransposons: possible source for evolutionary advantages

Recently, a novel phenomenon of horizontal gene transfer of helicase-encoding sequence from positive-stranded RNA viruses to LINE transposons in insect genomes was described. TRAS family transposons encoding an ORF2 protein, which comprised all typical functional domains and an additional helicase domain, were found to be preserved in many families during the evolution of the order Lepidoptera....

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Acquisition of Full-Length Viral Helicase Domains by Insect Retrotransposon-Encoded Polypeptides

Recent metagenomic studies in insects identified many sequences unexpectedly closely related to plant virus genes. Here we describe a new example of this kind, insect R1 LINEs with an additional C-terminal domain in their open reading frame 2. This domain is similar to NTPase/helicase (SF1H) domains, which are found in replicative proteins encoded by plant viruses of the genus Tobamovirus. We h...

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ژورنال

عنوان ژورنال: PeerJ

سال: 2017

ISSN: 2167-8359

DOI: 10.7717/peerj.3673